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MDR1 drug sensitivity in dogs

An inherited gene mutation, common in herding breeds, that impairs the body's ability to pump certain drugs out of the brain. Affected dogs can suffer serious or toxic reactions to normal doses of some medications, including some parasite treatments.

Breeds commonly associated with MDR1 drug sensitivity (3)

Related other conditions

Note. Breed associations are compiled from RVC VetCompass / AKC / PDSA and are indicative, not a diagnosis or veterinary advice. Browse all conditions or the breed directory.