MDR1 drug sensitivity in dogs
An inherited gene mutation, common in herding breeds, that impairs the body's ability to pump certain drugs out of the brain. Affected dogs can suffer serious or toxic reactions to normal doses of some medications, including some parasite treatments.
3 of the 155 breeds we track are commonly associated with MDR1 drug sensitivity, including Australian Shepherd, Shetland Sheepdog, Collie. Across these breeds median lifespans range from 13.3 to 13.7 years.
MDR1 drug sensitivity in dogs: quick facts
- Type
- other condition
- Breeds affected
- 3 of the 155 breeds we track
- Severity (as scored)
- Standard hereditary condition
Plain-English definitions of these terms are on the glossary. On the Breed Health Score, MDR1 drug sensitivity is weighted as a standard hereditary condition within a breed's overall burden. This describes how our data weights the condition, not a diagnosis.
Breeds commonly associated with MDR1 drug sensitivity (3), ranked by health score
Related other conditions
Products that may help
General care products for dogs prone to MDR1 drug sensitivity. Browse on Amazon → Ad
Note. Breed associations are compiled from RVC VetCompass / AKC / PDSA and are indicative, not a diagnosis or veterinary advice. Browse all conditions or the breed directory.